Fontem paginae Moclobemidum inspicere

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{| class="wikitable floatright" width=25%
! style="background-color:#e55575;" | Moclobemidum
|- style="text-align: center"
| <div style="position: relative;">[[Fasciculus:moclobemide.svg|200px|Moclobemidum]]
|- style="text-align: center"
| <div style="position: relative;">[[Fasciculus:Moclobemide3Dan.gif|200px|Moclobemidum]]
|-
! style="background-color:#a5a5a5;" | Natura pharmacologica
|-
| <small>[[Tempus semivitae biologicum]]: 1.5 — 4.0 h</small>
|}
'''Moclobemidum''' est substantia psychoanaleptica, antidepressiva et inhibitor [[monoaminorum oxidasis|monoaminorum oxidasium A]] reversiblis. 

== Natura Moclobemidi ==
=== Natura chemica ===
Moclobemidum est benzamidum, morpholinum et chloroarena. Structura eius chemica est 4-chloro-N-(2-morpholin-4-ylethyl)benzamidum. 

Moclobemidum in aqua male solvitur. 
Massa molaris est 268.739 g/mol. 
In [[Systema classificationis Anatomicum Therapeuticum Chemicumque|codice ATC]] in classe [[Codex ATC N06AG|N06AG]]02 est.

=== Natura pharmacologica ===
=== Pharmacodynamica ===
Moclobemidum est inhibitor [[monoaminorum oxidasis|monoaminorum oxidasium A]] reversiblis. Ex eo enim in [[Vesicula synaptica|vesiculis synapticis]] [[Neuron|neuronisque]] ipsis concentrationes substantiarum et [[Noradrenalinum|noradrenalini]] et [[Dopaminum|dopamini]] et praecipue [[Serotoninum|serotonini]] auget. 

=== Pharmacocinetica ===
[[Tempus semivitae biologicum]] <math>t_{\frac{1}{2}}</math>.<ref>http://goldbook.iupac.org/B00658.html</ref> circa 1,5 h (in senectute 4 h) est. 
Moclobemidum substratum [[Cytochroma P450|cytochromatis]] [[CYP2C19]], inhibtor cytochromum CYP2C19 et [[CYP2D6]] et [[CYP1A2]] est. 
Excretio fit per urinas (>95%) et biles (<5%). 

== Effectus Moclobemidi ==
=== Reactiones adversae ===
{{Main| Adversa drogae reactio}}
Saepe: 
* Nausea
* Insomnia
* Xerostomia (=Siccitas oris)
* Dysequilibrium

{{NexInt}} 
* [[Depressio (psychiatria)|Depressio]]
* [[Pharmacologia]]

== Notae ==
<references/>

[[Categoria:Monoaminorum oxidasis inhibitores]]
[[Categoria:Antidepressiva]]